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Methyl 4-methoxysalicylate
  • Chemical Name: Methyl 4-methoxysalicylate
  • CAS No.: 5446-02-6

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1.What is the Methyl 4-methoxysalicylate ?

Methyl 4-methoxysalicylate (methyl 2-hydroxy-4-methoxybenzoate) was used in the enantioselective synthesis of (+)-coriandrone A and B, two bioactive natural products.

methyl 2,4-dihydroxybenzoate
2150-47-2

methyl 2,4-dihydroxybenzoate

methyl iodide
74-88-4

methyl iodide

methyl 2, 4-dimethoxybenzoate
2150-41-6

methyl 2, 4-dimethoxybenzoate

4-methoxymethylsalicylate
5446-02-6

4-methoxymethylsalicylate

Conditions
Conditions Yield
methyl 2,4-dihydroxybenzoate; With sodium hydride; In tetrahydrofuran; at 20 ℃; for 24h; Inert atmosphere;
methyl iodide; In tetrahydrofuran; at 20 ℃; for 24h; Inert atmosphere;
9.8%
12.5%
methyl 2,4-dihydroxybenzoate
2150-47-2

methyl 2,4-dihydroxybenzoate

methyl iodide
74-88-4

methyl iodide

4-methoxymethylsalicylate
5446-02-6

4-methoxymethylsalicylate

Conditions
Conditions Yield
With potassium carbonate; In acetone; for 3h; Reflux;
92%
With potassium carbonate; In acetone; Reflux; Inert atmosphere;
90%
With potassium carbonate; In acetone; Reflux;
90%

2.What is the CAS number for Methyl 4-methoxysalicylate ?

The CAS number of Methyl 4-methoxysalicylate is 5446-02-6.

More information of Methyl 4-methoxysalicylate 5446-02-6 are:

CAS?Number

5446-02-6

Density

1.216 g/cm3

Melting Point

50-53 °C(lit.)

Boiling Point

288.6 °C at 760 mmHg

Flash Point

113.9 °C

Vapor Pressure

0.00134mmHg at 25°C

Refractive Index

1.4600 (estimate)

HS CODE

29189900

PSA

55.76000

LogP

1.18740

3.What are another words for Methyl 4-methoxysalicylate ?

Synonyms?for?Methyl 4-methoxysalicylate 5446-02-6:p-Anisicacid, 2-hydroxy-, methyl ester (6CI,7CI,8CI);2-Hydroxy-4-methoxybenzoic acidmethyl ester;Methyl 2-hydroxy-4-methoxybenzoate;Methyl4-methoxy-2-hydroxybenzoate;NSC 17154;

4.What is the molecular formula of Methyl 4-methoxysalicylate?

The chemical formula of ?Methyl 4-methoxysalicylate is?C9H10O4 which containing 9 Carbon atoms,10 Hydrogen atoms and 4 Oxygen atoms,and the molecular weight of??Methyl 4-methoxysalicylate?is 182.176.

5.What is Methyl 4-methoxysalicylate (5446-02-6) used for?

Methyl 4-methoxysalicylate, also known as methyl 2-hydroxy-4-methoxybenzoate, is a white to light yellow crystalline powder with unique chemical properties. It is a derivative of salicylic acid and possesses a methoxy group at the para position, which contributes to its distinct characteristics and potential applications.

InChI:InChI=1/C9H10O4/c1-12-6-3-4-7(8(10)5-6)9(11)13-2/h3-5,10H,1-2H3

Relevant articles related to Methyl 4-methoxysalicylate:

Article

Source

Highly efficient and chemoselective cleavage of prenyl ethers using ZrCl4/NaBH4

Suresh Babu,China Raju,Srinivas,Madhusudana Rao

, p. 2525 - 2528 (2003)

Catalytic Carbochlorocarbonylation of Unsaturated Hydrocarbons via C?COCl Bond Cleavage**

Boehm, Philip,Denton, Elliott H.,Fellert, Maximilian,Lee, Yong Ho,Morandi, Bill,Roediger, Sven

supporting information, p. 23435 - 23443 (2021/09/20)

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