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DIMETHYL 2,6-PYRIDINEDICARBOXYLATE
  • Chemical Name: DIMETHYL 2,6-PYRIDINEDICARBOXYLATE
  • CAS No.: 5453-67-8

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1.What is the DIMETHYL 2,6-PYRIDINEDICARBOXYLATE ?

Dimethyl 2,6-pyridinedicarboxylate may be used in the synthesis of:ditopic macrocycle having two xylyl rings linked by diethylene glycol and 2,6-pyridinediamide spacers, which acts as host molecule capable of forming complexes with diphenylurea derivativesN,N′-bis(2-aminoethyl)dipicoloinic acid diamide Schiff base1,1′-(2,6-bispyridyl)bis-3-(9-ethylcarbazole-3-yl)-1,3-propanedione

methanol
67-56-1

methanol

Pyridine-2,6-dicarboxylic acid
499-83-2

Pyridine-2,6-dicarboxylic acid

2,6-bis(methoxycarbonyl)pyridine
5453-67-8

2,6-bis(methoxycarbonyl)pyridine

Conditions
Conditions Yield
With thionyl chloride; for 3h; Heating;
100%
With thionyl chloride; for 3h; Heating / reflux;
100%
With sulfuric acid; at 75 ℃; for 24h;
100%
With sulfuric acid; at 75 ℃; for 24h;
100%
With sulfuric acid; for 24h; Reflux;
99%
With thionyl chloride; at 0 ℃; for 5h; Reflux; Inert atmosphere;
98%
With sulfuric acid; for 12h; Reflux;
98%
With hydrogenchloride; 2,2-dimethoxy-propane; for 4h; Heating;
97%
With sulfuric acid; for 48h; Heating;
96%
With sulfuric acid; for 18h; Heating;
96%
With sulfuric acid; for 48h; Reflux;
96%
With sulfuric acid; for 48h; Reflux;
96%
With sulfuric acid; Reflux;
96%
With sulfuric acid; for 18h; Heating;
96%
With sulfuric acid; Heating;
95%
With sulfuric acid; for 6h; Reflux;
95%
With thionyl chloride; for 3h; Schlenk technique; Inert atmosphere; Reflux;
95%
With sulfuric acid; for 12h; Reflux;
95%
With sulfuric acid; at 70 ℃; for 24h;
95%
With sulfuric acid; for 3h; Reflux;
94%
With sulfuric acid; Reflux;
94%
With sulfuric acid; Reflux;
92%
With sulfuric acid; for 9h; Inert atmosphere; Reflux;
91%
With sulfuric acid; for 3h; Reflux;
91%
With sulfuric acid; at 30 - 70 ℃;
91%
With thionyl chloride; for 18h; Reagent/catalyst; Inert atmosphere; Reflux;
91.4%
With sulfuric acid; for 3h; Reflux;
91.5%
With sulfuric acid; In methanol; at 20 ℃; for 3h; Reflux;
91%
With sulfuric acid; for 16h; Reflux;
90%
With thionyl chloride; at 0 ℃; for 14h; Cooling with ice; Reflux;
88%
With sulfuric acid; for 4h; Reflux;
87%
With acetyl chloride; at 30 - 90 ℃; for 20h;
86%
With acetyl chloride;
86%
With sulfuric acid; for 100h; Heating;
85%
With sulfuric acid; for 20h; Reflux;
85%
With sulfuric acid; Reflux;
85%
Pyridine-2,6-dicarboxylic acid; With thionyl chloride; for 72h; Reflux;
methanol; for 3h; Reflux;
85%
Pyridine-2,6-dicarboxylic acid; With thionyl chloride; In N,N-dimethyl-formamide; for 10h; Inert atmosphere; Schlenk technique; Reflux;
methanol; In N,N-dimethyl-formamide; for 1h; Inert atmosphere; Schlenk technique; Reflux;
85.1%
With sulfuric acid; at 80 ℃; for 3h;
85.2%
With sulfuric acid; at 70 ℃; for 48h;
83%
With sulfuric acid; at 67 ℃; for 13h;
83%
With thionyl chloride; at 0 - 65 ℃;
82%
With sulfuric acid; Reflux;
82%
With sulfuric acid; at 70 ℃;
81%
With sulfuric acid; at 70 ℃;
81%
With thionyl chloride; at 0 ℃; Inert atmosphere; Reflux;
80%
With sulfuric acid; for 48h; Inert atmosphere; Reflux;
80%
With sulfuric acid; for 24h; Heating;
79%
With sulfuric acid; at 70 ℃; for 48h;
78%
for 24h; Reflux;
78%
With sulfuric acid; at 85 ℃; for 24h;
77%
With sulfuric acid; at 20 - 90 ℃;
76%
With hydrogenchloride; 2,2-dimethoxy-propane;
75%
With sulfuric acid; for 18h; Reflux;
75%
With hydrogenchloride; 2,2-dimethoxy-propane; In water; at 100 ℃; for 4h;
73%
With sulfuric acid; for 4h; Reflux;
73%
With sulfuric acid; Heating;
73%
With sulfuric acid; for 48h; Reflux;
70%
With sulfuric acid; for 48h; Reflux;
68%
With sulfuric acid; for 48h; Reflux;
66%
With sulfuric acid; for 24h; Reflux;
30%
With sulfuric acid; Heating;
82.27 g
With acetyl chloride;
With sulfuric acid;
With hydrogen cation;
With sulfuric acid; Heating;
With thionyl chloride;
With sulfuric acid;
With acetyl chloride;
methanesulfonic acid; at 240 ℃; under 26252.6 Torr; Industry scale; Microwave irradiation;
With sulfuric acid; Heating;
With acetyl chloride; at 20 ℃; for 24h;
With acetyl chloride;
With thionyl chloride; at 20 ℃; for 24h;
With acetyl chloride;
With sulfuric acid; for 48h; Reflux;
With thionyl chloride; at 0 ℃; for 20h; Reflux;
With thionyl chloride; for 6h; Reflux;
With sulfuric acid; Reflux;
With sulfuric acid;
With sulfuric acid;
With sulfuric acid;
With sulfuric acid;
With thionyl chloride; for 4h; Reflux;
Pyridine-2,6-dicarboxylic acid
499-83-2

Pyridine-2,6-dicarboxylic acid

2,6-bis(methoxycarbonyl)pyridine
5453-67-8

2,6-bis(methoxycarbonyl)pyridine

Conditions
Conditions Yield
With methanol; thionyl chloride; for 16h; Reflux;
93%
With hydrogenchloride;
Multi-step reaction with 2 steps
1: thionyl chloride / Heating
2: Heating
With thionyl chloride;
Multi-step reaction with 4 steps
1: thionyl chloride / Heating
2: Heating
3: 1.) Et4 NBF4 / 1.) electrolysis, acetonitrile, 2.) acetonitrile, 24 h
4: Et4 NBF4 / 1.) electrolysis, acetonitrile, 2.) acetonitrile, 24 h
With thionyl chloride; N,N,N,N-tetraethylammonium tetrafluoroborate;
Multi-step reaction with 2 steps
1: THF / 24 h / Heating
2: 1 h / 0 °C
With tetrahydrofuran;
Multi-step reaction with 2 steps
1: phosphorus pentachloride
With phosphorus pentachloride;
Multi-step reaction with 2 steps
1: thionyl chloride / 3 h / Reflux
2: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 4 h / Reflux
With thionyl chloride; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran;
Multi-step reaction with 2 steps
1: thionyl chloride / 0.75 h / Cooling with ice; Reflux
2: 0.5 h / 0 °C / Reflux
With thionyl chloride;
Multi-step reaction with 2 steps
1: thionyl chloride / 12 h / 75 °C
2: 0.5 h / 65 °C
With thionyl chloride;
Multi-step reaction with 2 steps
1: thionyl chloride / 4 h / Reflux; Inert atmosphere; Schlenk technique
2: dichloromethane / 2 h / 20 °C / Inert atmosphere; Schlenk technique
With thionyl chloride; In dichloromethane;
Multi-step reaction with 2 steps
1: thionyl chloride / 6 h / 0 °C / Reflux; Inert atmosphere
2: 12 h / 0 °C / Reflux; Inert atmosphere
With thionyl chloride;
With thionyl chloride; In methanol; at 0 - 80 ℃; for 6h; Inert atmosphere;

2.What is the CAS number for DIMETHYL 2,6-PYRIDINEDICARBOXYLATE ?

The CAS number of DIMETHYL 2,6-PYRIDINEDICARBOXYLATE is 5453-67-8.

More information of DIMETHYL 2,6-PYRIDINEDICARBOXYLATE 5453-67-8 are:

CAS?Number

5453-67-8

Density

1.231 g/cm3

Melting Point

121-125 °C(lit.)

Boiling Point

321.7 °C at 760 mmHg

Flash Point

148.3 °C

Vapor Pressure

0.000293mmHg at 25°C

Refractive Index

1.516

HS CODE

29333990

PSA

65.49000

LogP

0.65480

Pka

-0.46±0.10(Predicted)

3.What are another words for DIMETHYL 2,6-PYRIDINEDICARBOXYLATE ?

Synonyms?for?DIMETHYL 2,6-PYRIDINEDICARBOXYLATE 5453-67-8:2,6-Pyridinedicarboxylicacid, dimethyl ester (6CI,7CI,8CI,9CI);2,6-Bismethoxycarbonylpyridine;2,6-Dicarbomethoxypyridine;2,6-Dipicolinic acid dimethyl ester;Dimethyl2,6-pyridinedicarboxylate;Dipicolinic acid dimethyl ester;NSC 18855;

4.What is the molecular formula of DIMETHYL 2,6-PYRIDINEDICARBOXYLATE?

The chemical formula of ?DIMETHYL 2,6-PYRIDINEDICARBOXYLATE is?C9H9NO4 which containing 9 Carbon atoms,9 Hydrogen atoms,1 Nitrogen atoms and 4 Oxygen atoms,and the molecular weight of??DIMETHYL 2,6-PYRIDINEDICARBOXYLATE?is 195.175.

5.What is DIMETHYL 2,6-PYRIDINEDICARBOXYLATE (5453-67-8) used for?

DIMETHYL 2,6-PYRIDINEDICARBOXYLATE, also known as dimethylpyridine-2,6-dicarboxylate, is an off-white solid with a calculated standard molar enthalpy of formation derived from the standard molar enthalpy of combustion. It is a chemical compound that serves as a key intermediate in the synthesis of various organic compounds.

InChI:InChI=1/C9H9NO4/c1-13-8(11)6-4-3-5-7(10-6)9(12)14-2/h3-5H,1-2H3

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