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5-Fluoroindole
  • Chemical Name:5-Fluoroindole
  • CAS No.:399-52-0

Manufacturer supply top purity 5-Fluoroindole 399-52-0 with GMP standards

  • Molecular Formula:C8H6FN
  • Molecular Weight:135.141
  • Appearance/Colour:off-white crystalline powder 
  • Melting Point:45-48 °C(lit.) 
  • Boiling Point:258 °C at 760 mmHg 
  • PKA:16.16±0.30(Predicted) 
  • Flash Point:109.9 °C 
  • PSA:15.79000 
  • Density:1.273 g/cm3 
  • LogP:2.30700 

5-Fluoroindole(Cas 399-52-0) Usage

Definition

ChEBI: An organofluorine compound that is the 5-fluoro derivative of indole.

InChI:InChI=1/C8H6FN/c9-7-1-2-8-6(5-7)3-4-10-8/h1-5,10H

399-52-0 Relevant articles

Metal–Organic Layers Hierarchically Integrate Three Synergistic Active Sites for Tandem Catalysis

Quan, Yangjian,Lan, Guangxu,Shi, Wenjie,Xu, Ziwan,Fan, Yingjie,You, Eric,Jiang, Xiaomin,Wang, Cheng,Lin, Wenbin

supporting information, p. 3115 - 3120 (2020/12/09)

We report the design of a bifunctional m...

Ruthenium-Catalyzed Dehydrogenation Through an Intermolecular Hydrogen Atom Transfer Mechanism

Huang, Lin,Bismuto, Alessandro,Rath, Simon A.,Trapp, Nils,Morandi, Bill

supporting information, p. 7290 - 7296 (2021/03/01)

The direct dehydrogenation of alkanes is...

Covalent Organic Frameworks toward Diverse Photocatalytic Aerobic Oxidations

Liu, Shuyang,Tian, Miao,Bu, Xiubin,Tian, Hua,Yang, Xiaobo

supporting information, p. 7738 - 7744 (2021/05/07)

Photoactive two-dimensional covalent org...

Applications of rare earth silicon amination material as catalyst in preparation of indole or indole derivative

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Paragraph 0043-0047, (2020/03/03)

The invention belongs to the technical f...

399-52-0 Process route

5-fluoroindol-2(3H)-one
56341-41-4

5-fluoroindol-2(3H)-one

5-fluoro-1H-indole
399-52-0

5-fluoro-1H-indole

Conditions
Conditions Yield
With bis(trimethylsilyl)amide yttrium(III); 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane; In toluene; at 120 ℃; for 36h; Inert atmosphere;
92%
With bis(trimethylsilyl)amide yttrium(III); 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane; In toluene; at 120 ℃; for 36h; Schlenk technique; Sealed tube; Inert atmosphere;
86%
trans-5-fluoro-β-dimethylamino-2-nitrostyrene
32989-58-5

trans-5-fluoro-β-dimethylamino-2-nitrostyrene

5-fluoro-1H-indole
399-52-0

5-fluoro-1H-indole

Conditions
Conditions Yield
With hydrogen; In benzene; for 21h; under 2327.23 Torr;
60%
With nickel; hydrazine; In methanol;
In benzene;

399-52-0 Upstream products

  • 399-76-8
    399-76-8

    5-fluoroindole-2-carboxylic acid

  • 32989-58-5
    32989-58-5

    trans-5-fluoro-β-dimethylamino-2-nitrostyrene

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    tert-butyl 2-[(E)-2-chloroethenyl]-4-fluorophenylcarbamate

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    7-bromo-5-fluoro-1H-indole

399-52-0 Downstream products

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    343-90-8

    3-dimethylaminomethyl-5-fluoroindole

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    methyl 2-((diphenylmethylene)amino)-3-(5-fluoro-1H-indol-3-yl)propanoate

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    benzyl 8-fluoro-3,4-dimethylpyrrolo<3,2-b>carbazole-2-carboxylate

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    6-fluoro-1,4-dimethyl-9-H-carbazole