Home >Pharmaceutical> 5-Fluoroindole
- Chemical Name:5-Fluoroindole
- CAS No.:399-52-0
Manufacturer supply top purity 5-Fluoroindole 399-52-0 with GMP standards
- Molecular Formula:C8H6FN
- Molecular Weight:135.141
- Appearance/Colour:off-white crystalline powder
- Melting Point:45-48 °C(lit.)
- Boiling Point:258 °C at 760 mmHg
- PKA:16.16±0.30(Predicted)
- Flash Point:109.9 °C
- PSA:15.79000
- Density:1.273 g/cm3
- LogP:2.30700
5-Fluoroindole(Cas 399-52-0) Usage
|
Definition |
ChEBI: An organofluorine compound that is the 5-fluoro derivative of indole. |
InChI:InChI=1/C8H6FN/c9-7-1-2-8-6(5-7)3-4-10-8/h1-5,10H
399-52-0 Relevant articles
Metal–Organic Layers Hierarchically Integrate Three Synergistic Active Sites for Tandem Catalysis
Quan, Yangjian,Lan, Guangxu,Shi, Wenjie,Xu, Ziwan,Fan, Yingjie,You, Eric,Jiang, Xiaomin,Wang, Cheng,Lin, Wenbin
supporting information, p. 3115 - 3120 (2020/12/09)
We report the design of a bifunctional m...
Ruthenium-Catalyzed Dehydrogenation Through an Intermolecular Hydrogen Atom Transfer Mechanism
Huang, Lin,Bismuto, Alessandro,Rath, Simon A.,Trapp, Nils,Morandi, Bill
supporting information, p. 7290 - 7296 (2021/03/01)
The direct dehydrogenation of alkanes is...
Covalent Organic Frameworks toward Diverse Photocatalytic Aerobic Oxidations
Liu, Shuyang,Tian, Miao,Bu, Xiubin,Tian, Hua,Yang, Xiaobo
supporting information, p. 7738 - 7744 (2021/05/07)
Photoactive two-dimensional covalent org...
Applications of rare earth silicon amination material as catalyst in preparation of indole or indole derivative
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Paragraph 0043-0047, (2020/03/03)
The invention belongs to the technical f...
399-52-0 Process route
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-
56341-41-4
5-fluoroindol-2(3H)-one
-
-
399-52-0
5-fluoro-1H-indole
| Conditions | Yield |
|---|---|
|
With
bis(trimethylsilyl)amide yttrium(III); 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane;
In
toluene;
at 120 ℃;
for 36h;
Inert atmosphere;
|
92% |
|
With
bis(trimethylsilyl)amide yttrium(III); 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane;
In
toluene;
at 120 ℃;
for 36h;
Schlenk technique;
Sealed tube;
Inert atmosphere;
|
86% |
-
-
32989-58-5
trans-5-fluoro-β-dimethylamino-2-nitrostyrene
-
-
399-52-0
5-fluoro-1H-indole
| Conditions | Yield |
|---|---|
|
With
hydrogen;
In
benzene;
for 21h;
under 2327.23 Torr;
|
60% |
|
With
nickel; hydrazine;
In
methanol;
|
|
|
In
benzene;
|
399-52-0 Upstream products
-
399-76-8
5-fluoroindole-2-carboxylic acid
-
32989-58-5
trans-5-fluoro-β-dimethylamino-2-nitrostyrene
-
908600-91-9
tert-butyl 2-[(E)-2-chloroethenyl]-4-fluorophenylcarbamate
-
408355-23-7
7-bromo-5-fluoro-1H-indole
399-52-0 Downstream products
-
343-90-8
3-dimethylaminomethyl-5-fluoroindole
-
132659-94-0
methyl 2-((diphenylmethylene)amino)-3-(5-fluoro-1H-indol-3-yl)propanoate
-
143772-66-1
benzyl 8-fluoro-3,4-dimethylpyrrolo<3,2-b>carbazole-2-carboxylate
-
128612-26-0
6-fluoro-1,4-dimethyl-9-H-carbazole