- Chemical Name: 4-Chlorobenzeneacetyl chloride
- CAS No.: 25026-34-0
Manufacturer supply 4-Chlorobenzeneacetyl chloride 25026-34-0 with sufficient stock and high standard
- Molecular Formula: C8H6Cl2O
- Molecular Weight: 189.041
- Appearance/Colour: clear yellow to brown liquid
- Vapor Pressure: 0.017mmHg at 25°C
- Refractive Index: n20/D 1.5510(lit.)
- Boiling Point: 254.7 °C at 760 mmHg
- Flash Point: 103 °C
- PSA： 17.07000
- Density: 1.324 g/cm3
- LogP: 2.64790
4-Chlorobenzeneacetyl chloride(Cas 25026-34-0) Usage
InChI:InChI=1/C8H6Cl2O/c9-7-3-1-6(2-4-7)5-8(10)11/h1-4H,5H2
25026-34-0 Relevant articles
Synthesis and in vitro platelet aggregation and TP receptor binding studies on bicyclic 5,8-ethanooctahydroisoquinolines and 5,8-ethanotetrahydroisoquinolines
Saha, Shankar L,Roche, Victoria F,Pendola, Kathleen,Kearley, Mark,Lei, Longping,Romstedt, Karl J,Herdman, Mark,Shams, Gamal,Kaisare, Vivek,Feller, Dennis R
, p. 2779 - 2793 (2002)
Eighteen novel bicyclic 1-substituted be...
Design of dual MMP-2/HDAC-8 inhibitors by pharmacophore mapping, molecular docking, synthesis and biological activity
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, p. 72373 - 72386 (2015)
Recent analyses have highlighted the pro...
Design, Synthesis, and Biological Evaluation of Pyrazole Derivatives
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, p. 673 - 679 (2016)
In this in vitro study, a series of nove...
Synthesis and peripheral substituent effects of bay-annulated indigo derivatives
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, p. 2913 - 2916 (2018)
In this study, indolo-naphthyridine-6,13...
Synthesis, Characterization and Antimicrobial Activity of N-2-(4-Chlorophenyl)acetyl Derivatives of (S)-Amino Acids
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, p. 381 - 384 (2020/01/08)
This paper reports the synthesis, charac...
Synthesis and in vitro anti-platelet aggregation activities of 2-methoxy-5-arylamido-N-(pyridin-3-yl-methyl)benzamides
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, (2018/12/11)
In order to discover novel compounds wit...
Preparation of Organic Nitrates from Aryldiazoacetates and Fe(NO3)3·9H2O
Thurow, Samuel,Fernandes, Alessandra A. G.,Quevedo-Acosta, Yovanny,De Oliveira, Matheus F.,De Oliveira, Marcelo G.,Jurberg, Igor D.
supporting information, p. 6909 - 6913 (2019/09/12)
A thermal protocol is reported for the f...
Discovery and evolution of aloperine derivatives as novel anti-filovirus agents through targeting entry stage
Zhang, Xin,Liu, Qiang,Zhang, Na,Li, Qian–Qian,Liu, Zhan–Dong,Li, Ying–Hong,Gao, Li–Mei,Wang, You–Chun,Deng, Hong–Bin,Song, Dan–Qing
, p. 45 - 55 (2018/03/21)
Preventing filoviruses in the entry stag...
25026-34-0 Process route
-
-
1878-66-6
4-chlorophenylacetic Acid
-
-
79-37-8
oxalyl dichloride
-
-
25026-34-0
4-chlorophenacetyl chloride
| Conditions | Yield |
|---|---|
|
In
N-methyl-acetamide; dichloromethane;
|
-
-
3282-33-5
1-(4-chlorophenyl)-2-diazoethanone
-
-
25026-34-0
4-chlorophenacetyl chloride
| Conditions | Yield |
|---|---|
|
Multi-step reaction
with
2
steps
1: aq. Ag2
O / dioxane
2: (COCl)2; DMF / CH2
Cl2
With
oxalyl dichloride; N,N-dimethyl-formamide; silver(l) oxide;
In
1,4-dioxane; dichloromethane;
1: Rearrangement / 2: Chlorination;
|
25026-34-0 Upstream products
-
1878-66-6
4-chlorophenylacetic Acid
-
622-95-7
4-chlorobenzyl bromide
-
873-76-7
para-Chlorobenzyl alcohol
-
140-53-4
p-chlorobenzyl cyanide
25026-34-0 Downstream products
-
19202-19-8
2-(4-chlorophenyl)-1-(pyrrolidin-1-yl)-ethanone
-
99931-95-0
2-(4-chlorophenyl)-1-morpholinoethanone
-
100623-07-2
(4-chloro-phenyl)-thioacetic acid S -phenyl ester
-
93653-47-5
2-(4-chloro-phenyl)-N ,N -diethyl-2-pyridin-2-yl-acetamide