- Chemical Name: N,N'-Bis(benzyloxycarbonyl)-L-cystine
- CAS No.: 6968-11-2
Factory supply good quality N,N'-Bis(benzyloxycarbonyl)-L-cystine 6968-11-2 with stock
- Molecular Formula: C22H24N2O8S2
- Molecular Weight: 508.573
- Vapor Pressure: 1.11E-24mmHg at 25°C
- Melting Point: 118-122 °C
- Refractive Index: -91 ° (C=8.8, AcOH)
- Boiling Point: 766.1 °C at 760 mmHg
- PKA: 3.15±0.10(Predicted)
- Flash Point: 417.1 °C
- PSA： 201.86000
- Density: 1.422 g/cm3
- LogP: 3.90880
N,N'-Bis(benzyloxycarbonyl)-L-cystine(Cas 6968-11-2) Usage
InChI:InChI=1/C22H24N2O8S2/c25-19(26)17(23-21(29)31-11-15-7-3-1-4-8-15)13-33-34-14-18(20(27)28)24-22(30)32-12-16-9-5-2-6-10-16/h1-10,17-18H,11-14H2,(H,23,29)(H,24,30)(H,25,26)(H,27,28)/t17-,18-/m0/s1
6968-11-2 Relevant articles
Visible-Light-Mediated S?H Bond Insertion Reactions of Diazoalkanes with Cysteine Residues in Batch and Flow
Chen, Lin,Cui, Yu-Sheng,Duan, Xiu,Guo, Kai,Qin, Long-Zhou,Qiu, Jiang-Kai,Sun, Qi,Yuan, Xin,Zhuang, Kai-Qiang
supporting information, p. 5093 - 5104 (2020/09/23)
We describe the application of S?H bond ...
Highly Selective Sub-Nanomolar Cathepsin S Inhibitors by Merging Fragment Binders with Nitrile Inhibitors
Schade, Markus,Merla, Beatrix,Lesch, Bernhard,Wagener, Markus,Timmermanns, Simone,Pletinckx, Katrien,Hertrampf, Torsten
supporting information, p. 11801 - 11808 (2020/11/26)
Pharmacological inhibition of cathepsin ...
Application of a novel small scale UV LED photochemical batch reactor for the thiol-yne reaction
Griebenow, Nils,Br?se, Stefan,Dilmac, Alica M.
, p. 54301 - 54303 (2015/07/01)
The application of a novel small scale U...
Glycopolypeptides with a redox-triggered helix-to-coil transition
Kramer, Jessica R.,Deming, Timothy J.
supporting information; experimental part, p. 4112 - 4115 (2012/04/10)
Conformation-switchable glycopolypeptide...
6968-11-2 Process route
-
-
56-89-3
L-cystine
-
-
501-53-1,94274-21-2
benzyl chloroformate
-
-
6968-11-2
N,N'-bis(benzyloxycarbonyl)-L-cystine
| Conditions | Yield |
|---|---|
|
With
sodium hydrogencarbonate;
In
water;
at 20 ℃;
|
99%
|
|
L-cystine; benzyl chloroformate;
With
sodium hydroxide;
In
tetrahydrofuran; water;
at 20 ℃;
for 3.25h;
pH=10;
Cooling with ice;
Inert atmosphere;
With
hydrogenchloride;
In
water;
pH=2;
Inert atmosphere;
|
98%
|
|
With
sodium hydroxide;
at 0 ℃;
for 4h;
|
72%
|
|
With
sodium hydroxide;
In
benzene;
at 20 ℃;
for 3h;
pH=8 - 9;
|
71%
|
|
With
sodium hydroxide;
In
toluene;
at 0 ℃;
for 4h;
|
68.9%
|
|
|
50%
|
|
With
sodium hydroxide;
unter Kuehlung;
|
|
|
|
|
|
With
sodium hydroxide;
pH 10-12;
|
21.86 g
|
|
With
sodium hydroxide;
In
1,4-dioxane; water;
at 0 ℃;
for 3h;
pH=9;
|
|
|
L-cystine;
With
sodium hydroxide;
In
tetrahydrofuran; water;
pH=10;
benzyl chloroformate;
In
tetrahydrofuran; water;
at 0 ℃;
for 3h;
pH=10;
|
-
-
96289-13-3,53907-29-2
N-benzyloxycarbonyl-L-cysteine
-
-
6968-11-2
N,N'-bis(benzyloxycarbonyl)-L-cystine
| Conditions | Yield |
|---|---|
|
With
[bis(acetoxy)iodo]benzene;
In
dichloromethane;
for 0.0833333h;
Ambient temperature;
|
90%
|
|
With
1,2-Diiodoethane; triethylamine;
In
ethanol;
|
|
|
With
2-benzyl-2-(dimethylamino)-1-phenyl-butan-1-one; Propargylamine;
In
methanol;
for 1h;
UV-irradiation;
Inert atmosphere;
|
6968-11-2 Upstream products
-
56-89-3
L-cystine
-
501-53-1
benzyl chloroformate
-
96289-13-3
N-benzyloxycarbonyl-L-cysteine
-
91285-94-8
O-benzyl S-(pyridin-2-yl)carbonothioate
6968-11-2 Downstream products
-
23926-58-1
N,N'-Bis-benzyloxycarbonyl-cystin-diethylester
-
7249-75-4
N,N'-Dicarbobenzyloxy-L-cystinyldiamid
-
140209-96-7
C64 H80 N2 O16 S2
-
140209-98-9
C66 H78 F2 N2 O16 S2